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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM48
All Species:
4.85
Human Site:
S619
Identified Species:
10.67
UniProt:
Q9BTX1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTX1
NP_060557.2
674
76305
S619
S
S
K
P
P
R
I
S
G
S
L
V
D
T
S
Chimpanzee
Pan troglodytes
XP_513417
776
87618
S721
S
S
K
P
P
R
T
S
G
S
L
V
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001091911
530
59703
R483
Q
L
I
R
R
G
P
R
L
W
T
S
A
S
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCB1
673
75391
S620
K
P
P
R
A
S
G
S
L
V
D
T
S
Y
K
Rat
Rattus norvegicus
Q6AXN4
673
75694
S620
K
P
P
R
T
S
G
S
L
V
D
T
S
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518195
431
47121
V382
L
S
K
R
A
L
I
V
Y
F
F
S
K
H
P
Chicken
Gallus gallus
XP_001235442
684
77153
G630
S
K
P
P
R
S
S
G
S
L
V
D
T
S
Y
Frog
Xenopus laevis
Q6AX31
660
74320
C613
G
S
L
L
D
S
S
C
K
T
L
R
F
S
L
Zebra Danio
Brachydanio rerio
Q7SZC5
671
74423
V616
S
S
K
P
A
R
T
V
C
S
M
G
D
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCG4
578
65368
I531
S
V
I
G
N
I
R
I
S
S
S
S
F
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784037
756
85199
P708
A
T
E
V
M
D
T
P
S
S
G
T
T
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
76.4
N.A.
N.A.
87
86.9
N.A.
20.4
67.8
56.8
53.5
N.A.
22.7
N.A.
N.A.
28.1
Protein Similarity:
100
86.2
77.3
N.A.
N.A.
92.1
92.5
N.A.
33.5
79.3
72.4
72.2
N.A.
43.4
N.A.
N.A.
45.3
P-Site Identity:
100
93.3
0
N.A.
N.A.
6.6
6.6
N.A.
20
13.3
13.3
46.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
6.6
N.A.
N.A.
6.6
6.6
N.A.
20
26.6
26.6
66.6
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
28
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
0
0
19
10
28
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
0
19
0
0
% F
% Gly:
10
0
0
10
0
10
19
10
19
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
19
0
0
10
19
10
0
0
0
0
0
0
0
% I
% Lys:
19
10
37
0
0
0
0
0
10
0
0
0
10
0
19
% K
% Leu:
10
10
10
10
0
10
0
0
28
10
28
0
0
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
19
28
37
19
0
10
10
0
0
0
0
0
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
37
19
28
10
10
0
0
0
10
0
0
0
% R
% Ser:
46
46
0
0
0
37
19
37
28
46
10
28
19
37
19
% S
% Thr:
0
10
0
0
10
0
28
0
0
10
10
28
19
19
19
% T
% Val:
0
10
0
10
0
0
0
19
0
19
10
19
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
19
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _